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Saget directed the 1996 TV movie For Hope, about a young woman with scleroderma based on Gay's experience, which helped raise awareness of the disease. Watching Gay's struggle with the disease pushed Saget to become a dedicated advocate for more research into a cure. My family is still having post-traumatic stress disorder. "It is incredibly painful to have a loved one experience a condition like this. "She needed so much help," he told NIH Medline Plus.
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Saget's sister was diagnosed at age 44, and died two years later, in 1994. RELATED: Bob Saget, Star of Full House and America's Funniest Home Videos, Dies at 65
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There is no direct cure for scleroderma, and instead different treatments that can target the various symptoms of the disease, such as steroid creams for the skin inflammation, blood pressure medications for any lung or kidney problems, immune suppressants and over-the-counter pain relievers. And if scleroderma reaches the digestive system, it can cause heartburn, difficulty swallowing, bloating and diarrhea. Scarring of heart tissue could lead to congestive heart failure. Scleroderma in the kidneys can lead to elevated blood pressure and rapid kidney failure. The lungs can develop scar tissue which can make it harder to breathe.
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But in severe forms, called systemic scleroderma, the disease spreads through other systems in the body and "can damage your blood vessels and internal organs, such as the heart, lungs and kidneys," according to NIH.Īnd if scleroderma spreads through the body, it affects each organ in different ways. In mild cases, scleroderma just affects the skin. The disease causes the skin to form hard, tight patches that can grow or shrink, and sometimes suddenly disappear. John Stamos, George Lopez, Ray Romano, Dave Chappelle, John Mayer and Robin Williams were among the friends who helped him.Scleroderma is a rare, autoimmune connective tissue and rheumatic disease that primarily causes inflammation in the skin, and can lead to inflammation in other parts of the body, according to the National Institutes of Health. Through laughter and star power, Saget raised more than $26 million for the Scleroderma Research Foundation. "It's so healthy to laugh, and I'm out there doing it and I know it's healing for people." "Humor is the only way my family survived," he said. You know, and being an actor, that's a very important thing if your hair gets out of place."Įven as he talked about the death of his sister, humor came in.
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"And it, I don't know how to explain it, but it felt like, I mean, I'm going to go all 'woo woo' here, but it felt like the soul going past us, literally felt it. "We were all in the room when she let out her last breath," Saget said. Her symptoms completely resolved after she started taking medication to suppress her immune system.īut when Gay Saget was diagnosed, much less was known about the disease and how to treat it. "I couldn't hold the small dental instruments to do root canals and my hands were swollen. My face started to swell up," Adams-Williams said. They were heavy as I was going up the steps.